Are ‘Clean’ Injectables Really A Thing?
So, is there such a thing as ‘clean’ injectables? The answer depends on how you define it. For Xeomin® — which has been nicknamed “naked Botox” — what sets it apart from other neurotoxins (Botox®, Dysport®, Jeuveau®) is its formulation. “Xeomin® is not linked to a stabilizing protein [like] Botox® is,” says Melissa Doft, MD, double board-certified plastic and reconstructive surgeon in New York City. As a result, it functions a bit differently. “When Botox® is injected, the protein is cleaved from the molecule and it binds to receptors blocking the transmission of nerve signals,” she explains. Since Xeomin® skips this step, it should, in theory, act faster. It also means a patient is less likely to build up antibody resistance to it over time.